11. Spieltag
| Datum | Heim | | Auswärts | Erg. | Tipp | Res. | G | U | V | 1 | X | 2 |
| 08.10.2021 18:00 | SV Lippstadt 08 | - | Wuppertaler SV | -:- | 0:1 | - | 19.93% | 24.61% | 55.46% | 5.02 | 4.06 | 1.80 |
| 08.10.2021 19:30 | Alemannia Aachen | - | FC Wegberg-Beeck | -:- | 1:0 | - | 45.54% | 28.09% | 26.38% | 2.20 | 3.56 | 3.79 |
| | SC Wiedenbrück | - | Rot Weiss Ahlen | -:- | 1:0 | - | 48.04% | 27.20% | 24.76% | 2.08 | 3.68 | 4.04 |
| 09.10.2021 14:00 | Bonner SC | - | VfB Homberg | -:- | 1:0 | - | 40.68% | 29.30% | 30.02% | 2.46 | 3.41 | 3.33 |
| | Preußen Münster | - | Fortuna Düsseldorf II | -:- | 2:1 | - | 50.93% | 23.84% | 25.23% | 1.96 | 4.20 | 3.96 |
| | Bor. Mönchengladbach II | - | Sportfreunde Lotte | -:- | 1:0 | - | 50.73% | 24.87% | 24.39% | 1.97 | 4.02 | 4.10 |
| | KFC Uerdingen 05 | - | Rot-Weiss Essen | -:- | 0:2 | - | 5.10% | 15.54% | 79.36% | 19.60 | 6.44 | 1.26 |
| | Rot-Weiß Oberhausen | - | SV Straelen | -:- | 2:1 | - | 56.38% | 22.67% | 20.94% | 1.77 | 4.41 | 4.77 |
| 12.10.2021 14:00 | FC Schalke 04 II | - | SC Fortuna Köln | -:- | 1:2 | - | 26.70% | 24.62% | 48.69% | 3.75 | 4.06 | 2.05 |
| 27.10.2021 14:00 | 1. FC Köln II | - | SV Rödinghausen | -:- | 2:1 | - | 39.78% | 24.47% | 35.74% | 2.51 | 4.09 | 2.80 |
Ergebnisse und Prognosen für alle Spieltage der Regional Liga West.
