15. Spieltag
| Datum | Heim | | Auswärts | Erg. | Tipp | Res. | G | U | V | 1 | X | 2 |
| 02.12.2021 21:00 | Ajax Amsterdam | - | Willem II Tilburg | -:- | 3:0 | - | 87.20% | 9.32% | 3.48% | 1.15 | 10.73 | 28.75 |
| 03.12.2021 20:00 | FC Groningen | - | PEC Zwolle | -:- | 1:0 | - | 62.07% | 23.29% | 14.63% | 1.61 | 4.29 | 6.83 |
| 04.12.2021 16:30 | PSV Eindhoven | - | FC Utrecht | -:- | 2:1 | - | 57.84% | 20.94% | 21.23% | 1.73 | 4.78 | 4.71 |
| 04.12.2021 18:45 | SC Cambuur-Leeuwarden | - | Vitesse Arnhem | -:- | 1:2 | - | 34.56% | 23.91% | 41.53% | 2.89 | 4.18 | 2.41 |
| 04.12.2021 21:00 | Heracles Almelo | - | SC Heerenveen | -:- | 2:1 | - | 40.70% | 24.32% | 34.98% | 2.46 | 4.11 | 2.86 |
| 05.12.2021 12:15 | RKC Waalwijk | - | NEC Nijmegen | -:- | 0:1 | - | 35.14% | 26.14% | 38.71% | 2.85 | 3.83 | 2.58 |
| 05.12.2021 14:30 | AZ Alkmaar | - | Sparta Rotterdam | -:- | 2:0 | - | 69.34% | 18.60% | 12.06% | 1.44 | 5.38 | 8.29 |
| | Go Ahead Eagles Deventer | - | FC Twente Enschede | -:- | 1:2 | - | 35.46% | 25.08% | 39.46% | 2.82 | 3.99 | 2.53 |
| 05.12.2021 16:45 | Feyenoord Rotterdam | - | Fortuna Sittard | -:- | 2:0 | - | 78.91% | 14.49% | 6.61% | 1.27 | 6.90 | 15.14 |
Ergebnisse und Prognosen für alle Spieltage der Eredivisie.
