1. Spieltag
| Datum | Heim | | Auswärts | Erg. | Tipp | Res. | G | U | V | 1 | X | 2 |
| 13.08.2021 20:00 | Go Ahead Eagles Deventer | - | SC Heerenveen | -:- | 0:1 | - | 15.55% | 27.08% | 57.37% | 6.43 | 3.69 | 1.74 |
| 14.08.2021 16:30 | RKC Waalwijk | - | AZ Alkmaar | -:- | 0:2 | - | 4.51% | 13.39% | 82.10% | 22.17 | 7.47 | 1.22 |
| 14.08.2021 18:45 | Heracles Almelo | - | PSV Eindhoven | -:- | 0:2 | - | 10.52% | 16.33% | 73.15% | 9.51 | 6.12 | 1.37 |
| 14.08.2021 20:00 | Fortuna Sittard | - | FC Twente Enschede | -:- | 1:2 | - | 33.50% | 25.35% | 41.16% | 2.99 | 3.95 | 2.43 |
| 14.08.2021 21:00 | Ajax Amsterdam | - | NEC Nijmegen | -:- | 2:0 | - | 90.45% | 8.34% | 1.21% | 1.11 | 11.99 | 82.48 |
| 15.08.2021 12:15 | SC Cambuur-Leeuwarden | - | FC Groningen | -:- | 0:1 | - | 14.23% | 29.89% | 55.89% | 7.03 | 3.35 | 1.79 |
| 15.08.2021 14:30 | PEC Zwolle | - | Vitesse Arnhem | -:- | 1:2 | - | 21.83% | 22.90% | 55.27% | 4.58 | 4.37 | 1.81 |
| | FC Utrecht | - | Sparta Rotterdam | -:- | 2:1 | - | 50.98% | 24.34% | 24.68% | 1.96 | 4.11 | 4.05 |
| 15.08.2021 16:45 | Willem II Tilburg | - | Feyenoord Rotterdam | -:- | 0:2 | - | 11.33% | 18.45% | 70.22% | 8.83 | 5.42 | 1.42 |
Ergebnisse und Prognosen für alle Spieltage der Eredivisie.
