10. Spieltag
| Datum | Heim | | Auswärts | Erg. | Tipp | Res. | G | U | V | 1 | X | 2 |
| 24.09.2021 19:00 | Hallescher FC | - | 1.FC Magdeburg | -:- | 0:1 | - | 31.42% | 25.73% | 42.85% | 3.18 | 3.89 | 2.33 |
| 25.09.2021 14:00 | Würzburger Kickers | - | SV Wehen Wiesbaden | -:- | 0:1 | - | 27.59% | 28.78% | 43.63% | 3.62 | 3.47 | 2.29 |
| | 1.FC Kaiserslautern | - | VfL Osnabrück | -:- | 1:2 | - | 32.51% | 24.62% | 42.87% | 3.08 | 4.06 | 2.33 |
| | FC Viktoria Köln | - | MSV Duisburg | -:- | 0:1 | - | 30.46% | 25.77% | 43.77% | 3.28 | 3.88 | 2.28 |
| | SV Meppen | - | 1.FC Saarbrücken | -:- | 0:1 | - | 25.20% | 25.60% | 49.19% | 3.97 | 3.91 | 2.03 |
| | SC Verl | - | TSV 1860 München | -:- | 0:1 | - | 29.51% | 25.58% | 44.91% | 3.39 | 3.91 | 2.23 |
| | Eintracht Braunschweig | - | SV Waldhof Mannheim | -:- | 1:0 | - | 36.55% | 28.06% | 35.40% | 2.74 | 3.56 | 2.82 |
| 26.09.2021 13:00 | Türkgücü München | - | Borussia Dortmund II | -:- | 1:2 | - | 24.45% | 24.23% | 51.32% | 4.09 | 4.13 | 1.95 |
| 26.09.2021 14:00 | FSV Zwickau | - | SC Freiburg II | -:- | 0:1 | - | 32.98% | 29.68% | 37.34% | 3.03 | 3.37 | 2.68 |
| 27.09.2021 19:00 | FC Viktoria 1889 Berlin | - | TSV Havelse | -:- | 1:0 | - | 62.55% | 23.61% | 13.84% | 1.60 | 4.24 | 7.23 |
Ergebnisse und Prognosen für alle Spieltage der 3. Liga.
