39. Spieltag
| Datum | Heim | | Auswärts | Erg. | Tipp | Res. | G | U | V | 1 | X | 2 |
| 21.05.2021 19:00 | Eintracht Stadtallendorf | - | FC Bayern Alzenau | -:- | 0:1 | - | 20.10% | 26.48% | 53.42% | 4.97 | 3.78 | 1.87 |
| | SV Elversberg | - | TSG Balingen | -:- | 2:0 | - | 75.70% | 16.18% | 8.12% | 1.32 | 6.18 | 12.32 |
| 22.05.2021 14:00 | VfR Aalen | - | Bahlinger SC | -:- | 1:0 | - | 38.27% | 26.19% | 35.54% | 2.61 | 3.82 | 2.81 |
| | FK Pirmasens | - | 1.FSV Mainz 05 II | -:- | 0:1 | - | 29.00% | 27.01% | 43.98% | 3.45 | 3.70 | 2.27 |
| | VfB Stuttgart II | - | FC Gießen | -:- | 2:1 | - | 53.97% | 23.13% | 22.90% | 1.85 | 4.32 | 4.37 |
| | TSV Schott Mainz | - | SSV Ulm 1846 | -:- | 0:2 | - | 6.75% | 15.85% | 77.40% | 14.82 | 6.31 | 1.29 |
| | KSV Hessen Kassel | - | SC Freiburg II | -:- | 0:2 | - | 12.14% | 19.85% | 68.01% | 8.24 | 5.04 | 1.47 |
| | FC 08 Homburg | - | TSV Steinbach | -:- | 1:2 | - | 25.55% | 23.43% | 51.03% | 3.91 | 4.27 | 1.96 |
| | TuS Rot-Weiß Koblenz | - | 1899 Hoffenheim II | -:- | 0:1 | - | 30.95% | 27.14% | 41.91% | 3.23 | 3.68 | 2.39 |
| | FSV Frankfurt | - | Kickers Offenbach | -:- | 0:1 | - | 24.19% | 24.56% | 51.25% | 4.13 | 4.07 | 1.95 |
| | FC Astoria Walldorf | - | SG Sonnenhof Großaspach | -:- | 1:0 | - | 47.40% | 25.57% | 27.03% | 2.11 | 3.91 | 3.70 |
Ergebnisse und Prognosen für alle Spieltage der Regional Liga Südwest.
